Elderly and Frail Face Severe Risks from New Weight-Loss Drug Side Effects, Doctors Warn
Doctors Warn of Bone and Muscle Loss Linked to Popular Weight-Loss Drugs
Weight-loss medications like OzPSempic, Wegovy, and Mounjaro may increase the risk of osteoporosis and fractures, according to the Royal Osteoporosis Society (ROS). Research suggests that up to 40% of weight lost using these GLP-1 agonist drugs could come from muscle and bone mass, raising concerns about long-term health impacts.
Key Risks Highlighted
GLP-1 drugs, used by over 500,000 people in the UK, help users lose up to 20% of their body weight. However, reduced bone density and muscle mass can weaken joints, heighten fracture risks, and accelerate osteoporosis—a condition causing brittle bones. Postmenopausal women are particularly vulnerable due to natural declines in bone-protecting estrogen.
Image Suggestion: A visual comparison of healthy vs. osteoporotic bone structure to illustrate bone density loss.
Expert Warnings
Julia Thomson, a specialist nurse at ROS, emphasized the need for awareness: “These drugs can deplete bone and muscle, increasing the risk of falls and fractures, which can be life-altering.” She stressed that prescriptions should follow thorough medical consultation.
Professor Carl Heneghan of Oxford University warned, “These drugs pose significant risks over time, especially for the elderly or frail. Preventing obesity through lifestyle changes should be prioritized over quick fixes.”
Image Suggestion: A person consulting a healthcare provider, symbolizing informed medical guidance.
Research Insights
A University of Liverpool study found that 40% of weight lost via GLP-1 drugs may stem from muscle and bone. Dr. Taher Mahmud, a bone health expert, advised users to prioritize nutrient-rich diets and weight-bearing exercises to mitigate risks.
Image Suggestion: A person engaging in strength training to highlight the importance of exercise for bone health.
Conclusion
While GPL-1 drugs offer significant weight-loss benefits, experts urge caution. Balancing medication with lifestyle strategies is crucial to safeguarding bone and muscle health, particularly for high-risk groups.
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